2017-03-31
BIOAFRICA & SATuRN

Newsletter, Jan-Mar 2017: 'Alarming' drug resistance levels, novel next generation sequencing method and the origin of HIV, SATuRN & CAPRISA workshop

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about our research work. In this Jan-Mar 2017 issue of our newsletter, we have included interesting open access publications, news, blogs, reports, tweets, and training information produced by our group.

2017-03-30
SATuRN & CAPRISA

SATuRN & CAPRISA 2017: HIV & TB Drug Resistance and Advanced Care Workshop

The workshop is targeted at clinicians, clinical virologists and nurses working in the public sector who are currently involved in the treatment of patients with HIV and TB in KwaZulu-Natal, South Africa.

2017-03-21
IDSE Infectious Diseases

CD4+ Count Not Useful to Assess ART Response in HTLV-1/HIV Coinfection

Patients coinfected with human T-cell lymphotropic virus 1 (HTLV-1) and HIV continue to have elevated CD4+ T-cell counts, even though there is no difference in their HIV viral load levels after antiretroviral therapy when compared with patients who just have HIV (Curr HIV Res 2017).

2017-03-17
UKZN & MRC Flagship

Seminar: Microbial genome-wide association studies: lessons from human GWAS

We cordially invites you to a seminar presented by Prof. Tulio de Oliveira, College of Health Sciences, UKZN & CAPRISA Research Associate, 17 March 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa

2017-03-17
Healio News

Prevalence of drug-resistant HIV reaches 'alarming levels' in Aruba

The prevalence of resistance to nonnucleoside reverse transcriptase inhibitors among HIV-infected individuals has increased to 'alarming levels' in Aruba, reaching 45% in 2015, see our recent publication at CID.

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration.
Rhee SY, Varghese V, Holmes SP, Van Zyl GU, Steegen K, Boyd MA, Cooper DA, Nsanzimana S, Saravanan S, Charpentier C, de Oliveira T, Etiebet MA, Garcia F, Goedhals D, Gomes P, Gunthard HF, Hamers RL, Hoffmann CJ, Hunt G, Jiamsakul A, Kaleebu P, Kanki P, Kantor R, Kerschberger B, Marconi VC, D'amour Ndahimana J, Ndembi N, Ngo-Giang-Huong N, Rokx C, Santoro MM, Schapiro JM, Schmidt D, Seu L, Sigaloff KCE, Sirivichayakul S, Skhosana L, Sunpath H, Tang M, Yang C, Carmona S, Gupta RK, Shafer RW., EBioMedicine (2017), :doi: 10.1016/j.ebiom.2017.03.024.

High Rates of Transmission of Drug-resistant HIV in Aruba Resulting in Reduced Susceptibility to the WHO Recommended First-line Regimen in Nearly Half of Newly Diagnosed HIV-infected Patients.
Hofstra LM, Rivas ES, Nijhuis M, Bank LEA, Wilkinson E, Kelly K, Mudrikova T, Schuurman R, de Oliveira T, de Kort J, Wensing AMJ, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix056.

Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis.
Collier D, Iwuji C, Derache A, de Oliveira T, Okesola N, Calmy A, Dabis F, Pillay D, Gupta RK, for ANRS 12249 TasP Study Group, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix015.

CD4+ T-cell count may not be a useful strategy to monitor antiretroviral therapy response in HTLV-1/HIV co-infected patients.
Vandormael A, Rego F, Danaviah S, Alcantara L, Boulware D, de Oliveira T, Current HIV Research (2017), :doi: 10.2174/1570162X15666170216114917.

Social disequilibrium and the risk of HIV acquisition: A multilevel study in rural KwaZulu-Natal Province, South Africa.
Tomita A, Vandormael AM, Barnighausen T, de Oliveira T, Tanser F, J Acquir Immune Defic Syndr. (2017), :10.1097/QAI.0000000000001349.

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