Introduction

BioAfrica presents the research, software and publications of Prof. Tulio de Oliveira and members of his research group.

Prof. Tulio de Oliveira research team is based the Wellcome Trust Africa Centre for Health and Population Studies, University of KwaZulu-Natal with some of its bioinformatics servers hosted at the South African Medical Research Council. Our  molecular violorogy laboratory is based at the DDMRI building, Nelson R Mandela School of Medicine, University of KwaZulu-Natal. BioAfrica also hosts the Southern African Treatment and Resistance Network (SATuRN) website.


Databases & Software Software & Resources Viruses Subtyping Tools Featured News:







HIV proteomics, HIV life cycle, proteins and information



HTLV-1 subtyping tool
HTLV-1 subtyping tool
HPV subtyping tool

Wellcome Trust Africa Centre and UKZN MRC Flagship Monthly Seminar Series
  Previous featured news








Open access pdf Publications (latest 5)

The origin of HTLV-1 in southern Bahia by phylogenetic, mtDNA and Beta-globin analysis.
Aleluia MM, Mello MAG,Alcantara LCJ, Rego FFA, Santos LPS, Galvao-Castro B, Goncalves MS, de Oliveira T, Marin LJ, Sousa SMB, Gadelha SR, Virology Reports (2015), :dx.doi.org/10.1016/j.virep.2015.05.002.

PANGEA-HIV: phylogenetics for generalised epidemics in Africa.
Pillay D, Herbeck J, Cohen MS, de Oliveira T, Fraser C, Ratmann O, Brown A-L, Kellam P, on behalf of the PANGEA-HIV Consortium, Lancet Infect Dis. (2015), 15(3):259-61.

Evidence of Long-Lived Founder Virus in Mother-to-Child HIV Transmission.
Danaviah S, de Oliveira T, Bland R, Viljoen J, Pillay S, Tuaillon E, Van de Perre P, Newell ML, PLoS One (2015), 10(3):e0120389.

Sequencing and phylogenetic analysis of near full-length HIV-1 subtypes A, B, G and unique recombinant AC and AD viral strains identified in South Africa.
Wilkinson E, Holzmayer V, Jacobs G, de Oliveira T, Brennan C, Hackett J Jr, Janse van Rensburg E, Engelbrecht S., AIDS Research and Human Retroviruses (2015), in press:.

The Impact of Drug Resistance Associated Amino Acid Changes on HIV-1 Subtype C on Susceptibility to Newer NNRTIs.
Basson AE, Rhee SY, Parry CM, El-Khatib Z, Charalambous S, De Oliveira T, Pillay D, Hoffmann C, Katzenstein D, Shafer RW, Morris L, Antimicrob Agents Chemother (2015), pii: AAC.04215-14:pii: AAC.04215-14.

All publications - Bioinformatics, genomics and drug resistance peer-reviewed papers on HIV, TB and other pathogens
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News News Section, printed & online media on HIV & TB drug resistance and bioinformatics (latest 5)

WTAC & MRC Flagship UKZN

Seminar: Clinical Impressions of HIV Pathogenesis & Vaccine Research

WTAC & MRC Flagship UKZN - 2015-06-19

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr Nigel Garrett from CAPRISA, 19 June 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


Science

MOLECULAR EPIDEMIOLOGY: HIV family trees reveal viral spread.

Science - 2015-06-12

By John Cohen, Science, 12 June 2015. New studies could aid public health efforts. Last week at the New York Academy of Sciences in New York City, researchers, public health specialists, and HIV/AIDS advocates discussed how to exploit the potential of the technique, called phylogenetic analysis - and the thorny ethical and legal issues it raises...


UNAIDS

Feature story: Understanding HIV through phylogenetic research

UNAIDS - 2015-06-08

Phylogenetic research 'the analysis of molecular sequencing data to study evolutionary relationships among groups and organisms' needs to be scaled up to end the AIDS epidemic, according to the participants at a symposium held on 4 June at the New York Academy of Sciences called HIV 2015: Using Phylogenetics to Enhance the HIV Response.


New York Academy of Sciences

HIV 2015: Using Phylogenetics to Enhance the HIV Response, New York, June 4, 2015

New York Academy of Sciences - 2015-06-04

A discussion meeting presented by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the Microbiology & Infectious Diseases Discussion Group at the New York Academy of Sciences on the use of phylogenetics to enhance HIV response.


WTAC & MRC Flagship UKZN

Seminar: Near Full Length Sequencing to Understand HIV & TB Epidemics In Africa In Real Time

WTAC & MRC Flagship UKZN - 2015-04-30

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Tulio de Oliveira, 30 April 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


All news...
Blogs on bioinformatics, HIV & TB drug resistance, treatment, community engagement and bioinformatics in Africa Twitter

Experience of 3 UKZN/Africa Centre students at the 7-week national bioinformatics workshop 2015

Author: Megan Druce, Zandile Sibisi & Sthembiso Msweli - 2015-04-23


Tale of 4 Cities in outlining researcher's strive towards a cure for HIV

Author: Siva Danaviah - 2014-10-14


Massive Open Online Courses: Huge potential for bioinformatics education

Author: Rachael Dellar - 2014-10-13


First impressions of a South African student working in Geneva as part of Swiss South Africa Joint Research Programme (SSAJRP)

Author: Megan Druce - 2014-10-07


HIV, TB and Malaria Molecular Diagnostics Workshop, Harare, Zimbabwe 2014

Author: Justen Manasa - 2014-10-06


Genetic study indicates two novel resistance loci for severe malaria in Africa

Author: Zakia Jeewa and Tulio de Oliveira - 2014-08-01


High-Level Cross-Resistance to ddI Observed in South African Children Failing an ABC- or d4T-Based 1st-Line Regimen

Author: Jennifer Giandhari and Joanna Ledwaba - 2014-07-25


15 minutes, All blogs...

Videos Videos Descriptions

YouTube Video

Completion of a world-class genomics lab at Africa Centre/UKZN, Durban, South Africa - Part III

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-08-06

This short video diary is the third in a series that traced the creation of a world class DNA genomic facility in the African continent that focuses on research on diseases that affect human health. This video shows the completion of genomics centre. It shows Illumina Miseq and Life Technologies Next Generation (NextGen) sequencing Facilities used in HIV & TB research.


YouTube Video

WTAC & UKZN Genomics Laboratory Construction - Video Diary Part II

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-04-05

This short video diary is the second in a series of movies that will trace the transformation of our existing laboratory into a world class DNA genomic facility. The second video provides an introduction to the robotics system and present our new bioinformatics facility. The genomics facility is based at the College of Health Sciences, University of KwaZulu-Natal and funded by the Wellcome Trust Africa Centre, South Africa MRC, UKZN, NRF and BMGF. This will be one of the first facilities in the African continent that focuses on research on diseases that affect human health.


YouTube Video

WTAC & UKZN Genomics Laboratory Construction - Video Diary Part I

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-03-13

This short video diary is the first in a series of four weekly movies that will trace the transformation of our existing laboratory into a world class DNA genomic facility. This will be one of the first facilities in the African continent that focuses on research on diseases that affect human health. The first video provides an introduction to the series, a pictorial tour of the current facilities and outlines the exciting renovation plans that are under way. The genomics facility is based at the College of Health Sciences, University of KwaZulu-Natal and funded by the Wellcome Trust Africa Centre, South Africa MRC, UKZN, NRF and BMGF


YouTube Video

HIV-1 Drug Resistance in Children in rural South Africa

Author: Siva Danaviah - Date: 2014-03-01

In a short interview, Dr. Siva Danaviah describes drug resistance patterns in HIV-infected children on antiretroviral therapy (ART) and its impact to inform public health policies in high prevalence settings. The aim of this study was to characterise the acquired drug resistance in HIV-infected children failing first-line ART in a decentralised rural HIV program in South Africa


YouTube Video

Justen Manasa PhD thesis summary

Author: Justen Manasa - Date: 2013-11-29

This is a 8 minutes video that summarizes the PhD thesis of Justen Manasa. This video cover the affordable and open accessible SATuRN/Life Tech genotyping method, SATuRN data curation process using RegaDB and a number of manuscripts on transmitted and acquired resistance in rural South Africa.


15 minutes, All videos...
Open access reports on HIV & TB drug resistance and bioinformatics in Africa HIV & TB Drug Resistance Clinical Cases Tutorial

SATuRN Collaborates on a Successful Molecular Diagnostics in HIV/AIDS and Tuberculosis in Zimbabwe, 6-9 Aug 2013

SATuRN 2013 report, date: 2013-08-21

Justen Manasa

SATuRN and Khethimpilo HIV Drug Resistance and Clinical Management Workshop Report, Durban, 11-12 July 2013

SATuRN 2013 report, date: 2013-08-01

Dean Solomon and Tulio de Oliveira

Major data analysis determines the trends of HIV-1 drug resistance mutations in South Africa.

SATuRN report 2013, date: 2013-07-01

Tulio de Oliveira

Transferring knowledge and skills to frontline medical personnel fighting the HIV & TB epidemics in rural South Africa

SATuRN 2013 report, date: 2013-03-16

Tulio de Oliveira, Justen Manasa, Richard Lessells

Bioafrica.net & SATuRN webpages received 186,746 visits in the past 12 months!

SATuRN 2013 report, date: 2013-02-26

Tulio de Oliveira

Clinical Case Study: The Diagnosis and Management of First-line Antiretroviral Treatment Failure

SATuRN 2012 report, date: 2013-01-16

Theresa Rossouw, Tulio de Oliveira & Richard Lessells

2nd Nurses and Health Care Workers Drug Resistance Training for the scale-up of resistance testing in the Free State Province, South Africa

SATuRN 2012 report, date: 2012-07-10

Dominique Goedhals & Cloete van Vuuren

SATuRN output, 15 minutes, All reports...

SATuRN output, 15 minutes, All cases...


Page design updated by Tulio de Oliveira, 2011