Introduction

BioAfrica presents the research, software and publications of Prof. Tulio de Oliveira and members of his research group.

Prof. Tulio de Oliveira research team is based the Wellcome Trust Africa Centre for Health and Population Studies, University of KwaZulu-Natal with some of its bioinformatics servers hosted at the South African Medical Research Council. Our  molecular violorogy laboratory is based at the DDMRI building, Nelson R Mandela School of Medicine, University of KwaZulu-Natal. BioAfrica also hosts the Southern African Treatment and Resistance Network (SATuRN) website.


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HIV proteomics, HIV life cycle, proteins and information



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Wellcome Trust Africa Centre and UKZN MRC Flagship Monthly Seminar Series
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Open access pdf Publications (latest 5)

HIV Drug Resistance Patterns at the Epicentre of the HIV-1 Epidemic in Kwazulu-Natal, South Africa 2003-2013.
Kiepiela P, Manasa J, Moosa M-Y, Moodley P, Gordon M, Parikh UM, Sunpath H, de Oliveira T, Ramjee G, J AIDS Clin Res (2014), 5:doi: 10.4172/2155-6113.1000299.

Phylogenetic studies of transmission dynamics in generalized HIV epidemics: An essential tool where the burden is greatest?.
Dennis AM, Herbeck JT, Brown AL, Kellam P, de Oliveira T, Pillay D, Fraser C, Cohen MS, J Acquir Immune Defic Syndr. (2014), in press:.

HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.
Tenzer S, Crawford H, Pymm P, Gifford R, Sreenu VB, Weimershaus M, de Oliveira T, Burgevin A, Gerstoft J, Akkad N, Lunn D, Fugger L, Bell J, Schild H, van Endert P, Iversen AK., Cell Reports (2014), 7:doi: 10.1016/j.celrep.2014.03.031.

Circulating Biomarkers of Immune Activation Distinguish Viral Suppression from Nonsuppression in HAART-Treated Patients with Advanced HIV-1 Subtype C Infection.
Malherbe G, Steel HC, Cassol S, de Oliveira T, Seebregts CJ, Anderson R, Cassol E, Rossouw TM., Mediators Inflamm. (2014), 2014:198413:doi: 10.1155/2014/198413.

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings.
Manasa J, Danaviah S, Pillay S, Padayachee P, Mthiyane H, Seebregts C, Rinke De Wit TF, Viljoen J, Katzenstein D, De Oliveira T , Journal of Visualized Experiments (JoVE) (2014), (85):e51242, doi:10.3791/51242.

All publications - Bioinformatics, genomics and drug resistance peer-reviewed papers on HIV, TB and other pathogens
...
News News Section, printed & online media on HIV & TB drug resistance and bioinformatics (latest 5)

WTAC, MRC & Stellenbosch

Seminar: Whole genome sequence interrogation of drug resistant Mycobacterium tuberculosis

WTAC, MRC & Stellenbosch - 2014-11-21

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Samantha Sampson, 21 November 2014, Susser & Stein Seminar Room, K-RITH building, Nelson R Mandela School of Medicine, Durban


SATuRN & AWACC

AWACC & SATuRN conference a success! Please see twitter summary

SATuRN & AWACC - 2014-10-13

SATuRN annual workshop run in partnership with AWACC (UKZN, NDoH & Harvard). In total 346 participants attended the two days workshop. The workshop discussions were also very good. Here, we summarize the Tweeter coverage of the event, which contains information on the topics discussed and questions raised.


WTAC, UCT & UKZN

Seminar: Transcriptional profiling in human tuberculosis

WTAC, UCT & UKZN - 2014-10-10

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Robert J Wilkinson, 10 October 2014, K-RITH building, Nelson R Mandela School of Medicine, Durban


SATuRN & Harvard

Doris Duke Annual Seminar for Medical Students from Harvard and UKZN

SATuRN & Harvard - 2014-10-09

Each year during AWAAC, the Doris Duke International Research Fellowship at Harvard Medical School sponsors a special seminar for medical students who will be attending the conference. During the seminar, invited faculty members discuss journals article that they select with a group of medical students from the US who are engaging in research in sub-Saharan Africa and a group of South African medical students from UKZN. This year 20-25 students will attend the seminar.


WTAC & Stellenbosch Univ

Seminar: ARV Therapy Initiated Before 2-Months-of-Age Reduces Transcriptionally Active HIV-1 DNA Persistence

WTAC & Stellenbosch Univ - 2014-09-19

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Gert Van Zyl, 19 September 2014, K-RITH building, Nelson R Mandela School of Medicine, Durban


All news...
Blogs on bioinformatics, HIV & TB drug resistance, treatment, community engagement and bioinformatics in Africa Twitter

Tale of 4 Cities in outlining researcher's strive towards a cure for HIV

Author: Siva Danaviah - 2014-10-14


Massive Open Online Courses: Huge potential for bioinformatics education

Author: Rachael Dellar - 2014-10-13


First impressions of a South African student working in Geneva as part of Swiss South Africa Joint Research Programme (SSAJRP)

Author: Megan Druce - 2014-10-07


HIV, TB and Malaria Molecular Diagnostics Workshop, Harare, Zimbabwe 2014

Author: Justen Manasa - 2014-10-06


Genetic study indicates two novel resistance loci for severe malaria in Africa

Author: Zakia Jeewa and Tulio de Oliveira - 2014-08-01


High-Level Cross-Resistance to ddI Observed in South African Children Failing an ABC- or d4T-Based 1st-Line Regimen

Author: Jennifer Giandhari and Joanna Ledwaba - 2014-07-25


The fidelity of HIV-1 RT is not as bad as we thought

Author: Adriaan E. Basson - 2014-07-24


15 minutes, All blogs...

Videos Videos Descriptions

YouTube Video

Completion of a world-class genomics lab at Africa Centre/UKZN, Durban, South Africa - Part III

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-08-06

This short video diary is the third in a series that traced the creation of a world class DNA genomic facility in the African continent that focuses on research on diseases that affect human health. This video shows the completion of genomics centre. It shows Illumina Miseq and Life Technologies Next Generation (NextGen) sequencing Facilities used in HIV & TB research.


YouTube Video

WTAC & UKZN Genomics Laboratory Construction - Video Diary Part II

Author: Prevashinee Padayachee - Date: 2014-04-05

This short video diary is the second in a series of movies that will trace the transformation of our existing laboratory into a world class DNA genomic facility. The second video provides an introduction to the robotics system and present our new bioinformatics facility. The genomics facility is based at the College of Health Sciences, University of KwaZulu-Natal and funded by the Wellcome Trust Africa Centre, South Africa MRC, UKZN, NRF and BMGF. This will be one of the first facilities in the African continent that focuses on research on diseases that affect human health.


YouTube Video

WTAC & UKZN Genomics Laboratory Construction - Video Diary Part I

Author: Prevashinee Padayachee - Date: 2014-03-13

This short video diary is the first in a series of four weekly movies that will trace the transformation of our existing laboratory into a world class DNA genomic facility. This will be one of the first facilities in the African continent that focuses on research on diseases that affect human health. The first video provides an introduction to the series, a pictorial tour of the current facilities and outlines the exciting renovation plans that are under way. The genomics facility is based at the College of Health Sciences, University of KwaZulu-Natal and funded by the Wellcome Trust Africa Centre, South Africa MRC, UKZN, NRF and BMGF


YouTube Video

HIV-1 Drug Resistance in Children in rural South Africa

Author: Siva Danaviah - Date: 2014-03-01

In a short interview, Dr. Siva Danaviah describes drug resistance patterns in HIV-infected children on antiretroviral therapy (ART) and its impact to inform public health policies in high prevalence settings. The aim of this study was to characterise the acquired drug resistance in HIV-infected children failing first-line ART in a decentralised rural HIV program in South Africa


YouTube Video

Justen Manasa PhD thesis summary

Author: Justen Manasa - Date: 2013-11-29

This is a 8 minutes video that summarizes the PhD thesis of Justen Manasa. This video cover the affordable and open accessible SATuRN/Life Tech genotyping method, SATuRN data curation process using RegaDB and a number of manuscripts on transmitted and acquired resistance in rural South Africa.


15 minutes, All videos...
Open access reports on HIV & TB drug resistance and bioinformatics in Africa HIV & TB Drug Resistance Clinical Cases Tutorial

SATuRN Collaborates on a Successful Molecular Diagnostics in HIV/AIDS and Tuberculosis in Zimbabwe, 6-9 Aug 2013

SATuRN 2013 report, date: 2013-08-21

Justen Manasa

SATuRN and Khethimpilo HIV Drug Resistance and Clinical Management Workshop Report, Durban, 11-12 July 2013

SATuRN 2013 report, date: 2013-08-01

Dean Solomon and Tulio de Oliveira

Major data analysis determines the trends of HIV-1 drug resistance mutations in South Africa.

SATuRN report 2013, date: 2013-07-01

Tulio de Oliveira

Transferring knowledge and skills to frontline medical personnel fighting the HIV & TB epidemics in rural South Africa

SATuRN 2013 report, date: 2013-03-16

Tulio de Oliveira, Justen Manasa, Richard Lessells

Bioafrica.net & SATuRN webpages received 186,746 visits in the past 12 months!

SATuRN 2013 report, date: 2013-02-26

Tulio de Oliveira

Clinical Case Study: The Diagnosis and Management of First-line Antiretroviral Treatment Failure

SATuRN 2012 report, date: 2013-01-16

Theresa Rossouw, Tulio de Oliveira & Richard Lessells

2nd Nurses and Health Care Workers Drug Resistance Training for the scale-up of resistance testing in the Free State Province, South Africa

SATuRN 2012 report, date: 2012-07-10

Dominique Goedhals & Cloete van Vuuren

SATuRN output, 15 minutes, All reports...

SATuRN output, 15 minutes, All cases...


Page design updated by Tulio de Oliveira, 2011