Dr. Veron Ramsuran

My work focus on host factors associating with HIV disease, with special interest on the Human Leukocyte Antigen (HLA) genes. I am also very interested epigenetics techniques such as CRISPR and DNA methylation.

Contact Details:

Email: Veron.ramsuran@gmail.com

Telephone: +27 (0) 31 260 4898

Background:

Dr. Veron Ramsuran graduated with a PhD from the University of KwaZulu-Natal where he examined host factors associating with HIV disease. He spent almost 70% of his PhD in two international laboratories, i.e. Fred Hutchinson Cancer Research Center and The University of Texas Health Science Center at San Antonio. After completion of his PhD he was recruited to join the Ragon Institute of MGH, MIT and Harvard as a post-doctoral research fellow, he had a joint affiliation with a contractor to the NIH and NCI. His appointment was under the mentorship of Dr. Mary Carrington. His work continued to focus on host factors associating with HIV disease, with special interest on the Human Leukocyte Antigen (HLA) genes. After completing 5 years in these institutes Dr. Ramsuran returned to South Africa where he is currently a Senior Lecturer within the University of KwaZulu-Natal.

Current Affiliations:

Group leader: KRISP - KwaZulu-Natal Research and Innovation Sequencing Platform, UKZN, Durban, South Africa.

- Senior Lecturer: School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Education:

- Post Doctorate: Ragon Institute of MGH, MIT and Harvard and National Cancer Institute (NCI) a division of the National Institute of Health (NIH) (2012-2016).

- PhD in Genetics: HIV Pathogenesis Programme and University of KwaZulu-Natal (2007-2011).

- MSc in Genetics: School of Life Sciences, University of KwaZulu-Natal (2006).


Videos Videos Descriptions

YouTube Video

Krisp - a next generation DNA sequencing research centre opens in Durban, South Africa - eTV news

Author: Tulio de Oliveira, Veron Ramsuran, Nicolette Crozier, Zandile Sibisi, Marcel Tongo, Benjamin Chimukangara, Thabiso Dlamini - Date: 2017-07-24

Krisp at South African eTV channel evenning news


Open access pdf Publications

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells.
Ramsuran V, Vivek Naranbhai, Amir Horowitz, Ying Qi, Maureen P. Martin, Yuko Yuki, Xiaojiang Gao, Victoria Walker-Sperling, Gregory Q. Del Prete, Douglas K. Schneider, Jeffrey D. Lifson, Jacques Fellay, Steven G. Deeks, Jeffrey N. Martin, James J. Goedert, Steven M. Wolinsky, Nelson L. Michael, Gregory D. Kirk, Susan Buchbinder, David Haas, Thumbi Ndung'u, Philip Goulder, Peter Parham, Bruce D. Walker, Jonathan M. Carlson and Mary Carrington, Science (2018), 359:86-90.

Hyperbilirubinemia in atazanavir-treated human immunodeficiency virus-infected patients: the impact of the UGT1A1*28 allele.
Naidoo A, Naidoo K, Ramsuran V, Reddy M, Padayatchi N, Pharmacogenomics and Personalized Medicine (2017), :doi: 10.2147/PGPM.S146787.

Sequence and Phylogenetic Analysis of the Untranslated Promoter Regions for HLA Class I Genes.
Ramsuran V, Hernandez-Sanchez PG, O'hUigin C, Sharma G, Spence N, Augusto DG, Gao X, Garcia-Sepulveda CA, Kaur G, Mehra NK, Carrington M,, J Immunol (2017), pii: 1601679:.

HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region.
Vince N, Li H, Ramsuran V, Naranbhai V, Duh FM, Fairfax BP, Saleh B, Knight JC, Anderson SK, Carrington M, Am J Hum Genet (2016), 99(6):1353-1358.

Epigenetic regulation of differential HLA-A allelic expression levels.
Ramsuran V, Kulkarni S, O'huigin C, Yuki Y, Augusto DG, Gao X, Carrington M, Hum Mol Genet (2015), 24(15):4268-75.

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK., Proc Natl Acad Sci U S A (2015), 112(34):E4762-71.

Expression of the CCR5 HIV co-receptor in women with genital schistosomiasis.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebo K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T, 16th ICID Abstracts / International Journal of Inf (2014), 21S:1-460.

Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebo K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T, PLoS One (2014), 9(6):e98593.

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.
Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M, Proc Natl Acad Sci U S A (2013), 110(51):20705-10.

Influence of variations in CCL3L1 and CCR5 on tuberculosis in a northwestern Colombian population.
Mamtani M, Mummidi S, Ramsuran V, Pham MH, Maldonado R, Begum K, Valera MS, Sanchez R, Castiblanco J, Kulkarni H, Ndung'u T, He W, Anaya JM, Ahuja SK, J Infect Dis (2011), 203(11):1590-4.

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.
Ramsuran V, Kulkarni H, He W, Mlisana K, Wright EJ, Werner L, Castiblanco J, Dhanda R, Le T, Dolan MJ, Guan W, Weiss RA, Clark RA, Karim SS, Ahuja SK, Ndung'u T, Clin Infect Dis. (2011), 52(10):1248-56.

Blogs Blogs Description & Link

bioafrica - Blogs from Bioafrica and SATuRN websites

Meeting of the Swiss, Swedes and South Africans minds

Author: Nicolette Crozier, Benjamin Chimukangara, Veron Ramsuran - 2017-07-25

bioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websitesbioafrica - News Section from Bioafrica and SATuRN websites
News News Description and Link

bioafrica - News Section from Bioafrica and SATuRN websites

KRISP Talks

Effect of DNA methylation on HIV disease

KRISP Talks - 2018-01-26

KRISP Talks by Dr. Veron Ramsuran, KRISP, UKZN & CAPRISA, 26 January 2018 (15:00 - 16:00), K-RITH building, Nelson R Mandela School of Medicine, UKZN, Durban, South Africa. All welcome!


KRISP News

Science Discovery: Biomarkers for HIV treatment

KRISP News - 2018-01-19

Mercury Reporter, Durban, KwaZulu-Natal, 19 Jan 2018: Scientists led an in ternational research team which discovered new genetic markers that identify why the onset of Aids appears to occur so quickly in some people after they are infected with HIV The study published in the journal Science (Ramsuran et al. Science 2018), sheds new light on how specific human genes can lead to a faster deterioration for people living with HIV who are not on treatment.


KRISP News

SA study reveals important link between genes and Aids

KRISP News - 2018-01-19

HIV/AIDS researchers have never understood why people infected with HIV developed Aids at different times? but now they suspect that it all has to do with their genes. A study by South African and US researchers (Ramsuran et al. Science 2018) has shed new light on how specific genes in people can lead to the faster progression of Aids-related illnesses in people living with HIV who are not on treatment.


KRISP News

Why some HIV-positive people develop AIDS quicker than others is now clearer

KRISP News - 2018-01-19

The study, published in the prestigious journal Science (Ramsuram et al. 2018), was led by South African scientists who, together with an international research team, discovered that a specific-type human leucocyte antigen (HLA) gene helps infected cells to evade the body's first line of defence


KRISP Papers

Science Editorial: Inhibiting natural killer cells in AIDS

KRISP Papers - 2018-01-04

The human leukocyte antigen (HLA) gene complex varies enormously among individuals and helps explain individual variation in immunity to infectious diseases. Ramsuran et al. (Science 2018) examined data from almost 10,000 HIV infections.


Why KRISP?

Why KRISP? KRISP challenges the status quo to create a scientific environment in South Africa that drives innovations & reverses the brain drain.

Why KRISP? - 2017-12-31

The Technology Innovation Agency (TIA) and UKZN have signed an agreement for the establishment of KRISP - the KwaZulu-Natal Research and Innovation Sequencing Platform.


KRISP News

Durban at the forefront of DNA research - KwaZulu-Natal Research and Innovation Sequencing Platform - KRISP

KRISP News - 2017-07-15

By Arthi Gopi, Independent on Saturday Newspaper - KRISP atrracts the brightest - Durban is leading the way in DNA research, having attracted some of the brightest minds in the science field, in a new state-of-the-art lab in the city.


KRISP News

KwaZulu-Natal Research and Innovation Sequencing Platform (KRISP) Established

KRISP News - 2017-07-12

The Technology Innovation Agency (TIA) and UKZN have signed an agreement for the establishment of KRISP - the KwaZulu-Natal Research and Innovation Sequencing Platform.


KRISP Talks

Seminar: Differential HLA-A Expression Levels and the Effect on HIV

KRISP Talks - 2017-01-27

KRISP Talks by Dr Veron Ramsuran, Senior Lecturer: College of Health Sciences, UKZN, 27 January 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa



Page design updated by Prof. Tulio de Oliveira, 2015