Southern African Treatment and Resistance Network (SATuRN)

SATuRN currently includes 24 research partners in southern Africa that support our initiatives. We have collated over 7,000 resistance genotypes linked to treatment and clinical information and host two of the best HIV drug resistance databases in the world (The Stanford HIV Drug Resistance Database and RegaDB Clinical Management and Drug resistance Database). To advance access to drug resistance testing to patients, providers and programs, we have been working with a network of academics laboratories to develop and implement a cheaper resistance genotype test. We have also delivered training in drug resistance testing and management to over 2,000 physician and nurses in southern Africa...


SATuRN Newsletters:
Information:

SATuRN newsletters:

Num 1 V.5 (Jan-Mar 2016)


Introduction:

SATuRN Mission/Vision

SATuRN Executive Summary

Who We Are: SATuRN Management, Participant Scientists, International Advisory Board, Funders


Information for Collaborators:

Manual of Operations (MoO) - reference to SATuRN organization, functions and access of data

Memorandum of Understanding (MoU) - deposit of data in SATuRN drug resistance databases (MSWord format)

Contributors Guidelines - website, newsletters and annual reports


Public Resources: HIV & TB Book and Online Databases

HIV & TB Drug Resistance and Clinical Management Casebook - Open access

SATuRN Stanford HIV Drug Resistance Database (HIVDB) -  Public Drug Resistance Databases in Southern Africa (de Oliveira et al. Nature 2010, 464:673)

SATuRN RegaDB Clinical Management Database - A Collaborative Clinical HIV Drug Resistance Database in Southern Africa


Open access pdf Publications (latest 5)

Sexual partnership age pairings and risk of HIV acquisition in rural South Africa.
Akulliana A, Bershteyna A, Kleina D, Vandormael A, Barnighausen T, Tanser F, AIDS (2017), :DOI:10.1097/QAD.0000000000001553.

Incidence rate estimation, periodic testing and the limitations of the mid-point imputation approach.
Vandormael A, Dobra A, Barnighausen T, de Oliveira T, Tanser F, International Journal of Epidemiology (2017), :doi.org/10.1093/ije/dyx134.

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration.
Rhee SY, Varghese V, Holmes SP, Van Zyl GU, Steegen K, Boyd MA, Cooper DA, Nsanzimana S, Saravanan S, Charpentier C, de Oliveira T, Etiebet MA, Garcia F, Goedhals D, Gomes P, Gunthard HF, Hamers RL, Hoffmann CJ, Hunt G, Jiamsakul A, Kaleebu P, Kanki P, Kantor R, Kerschberger B, Marconi VC, D'amour Ndahimana J, Ndembi N, Ngo-Giang-Huong N, Rokx C, Santoro MM, Schapiro JM, Schmidt D, Seu L, Sigaloff KCE, Sirivichayakul S, Skhosana L, Sunpath H, Tang M, Yang C, Carmona S, Gupta RK, Shafer RW., EBioMedicine (2017), :doi: 10.1016/j.ebiom.2017.03.024.

High Rates of Transmission of Drug-resistant HIV in Aruba Resulting in Reduced Susceptibility to the WHO Recommended First-line Regimen in Nearly Half of Newly Diagnosed HIV-infected Patients.
Hofstra LM, Rivas ES, Nijhuis M, Bank LEA, Wilkinson E, Kelly K, Mudrikova T, Schuurman R, de Oliveira T, de Kort J, Wensing AMJ, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix056.

Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis.
Collier D, Iwuji C, Derache A, de Oliveira T, Okesola N, Calmy A, Dabis F, Pillay D, Gupta RK, for ANRS 12249 TasP Study Group, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix015.

All publications - Bioinformatics, genomics and drug resistance peer-reviewed papers on HIV, TB and other pathogens
...
News News Section, printed & online media on HIV & TB drug resistance and bioinformatics (latest 5)

KRISP Training

11th Annual Workshop on Advanced Clinical Care - AIDS (AWACC), Durban, South Africa, 6-7 Sep 2017

KRISP Training - 2017-10-06

The workshop is targeted at 400 clinicians, clinical virologists and nurses working in the public sector who are currently involved in the treatment of patients with HIV and TB in KwaZulu-Natal, South Africa.


KRISP Training

X-meeting - 13th International Conference of the AB3C, Sao Pedro, Brazil, Oct 4-6, 2017

KRISP Training - 2017-09-04

Bioinformatics is now a strategic area for Brazil and all Latin America and, therefore, it is also strategic to the development of Science, Technology and Economy. The X-Meeting is a Brazilian event with international reach which has an average of 400 participants.


KRISP Training

22nd International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology (VEME), Lisbon, Portugal

KRISP Training - 2017-08-27

The workshop provides both theoretical and practical training in phylogenetic inference and evolutionary hypothesis testing. It is recognized as one of the best international virus bioinformatics courses. It covers sequence analysis, phylogenetics, phylodynamics methods and large scale methods for next-generation sequencing (NGS) analytics


KRISP Talks

A multi-centre analysis of internal migration and AIDS/TB and NCD-related mortality in Kenya and South Africa

KRISP Talks - 2017-08-23

KRISP Talks by Dr Carren Ginsburg, SAMRC/Wits Rural Public Health & Health Transitions Research Unit (Agincourt), 23 August 2017 (11am - midday), K-RITH building, Nelson R Mandela School of Medicine, UKZN, Durban, South Africa. All welcome!


KRISP Newsletter

KRISP Newsletter - July 2017: news, videos, blogs, publications and training events

KRISP Newsletter - 2017-08-01

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about KRISP work. In this July 2017 issue of our newsletter, we have included interesting news, videos, blogs, reports, tweets, publications and training events of KRISP


All news...
Blogs on bioinformatics, HIV & TB drug resistance, treatment, community engagement and bioinformatics in Africa Twitter

Bioinformaticians are pioneering the future of science

Author: Yumna Moosa - 2017-07-28


Meeting of the Swiss, Swedes and South Africans minds

Author: Nicolette Crozier, Benjamin Chimukangara, Veron Ramsuran - 2017-07-25


Megan Druce: from Cum Laude MSc to a Scholarship for a PhD in Germany...

Author: Megan Druce - 2016-04-18


Sthembiso Msweli: from Hlabisa to MSc and Further Promoted to Laboratory Manager...

Author: Sthembiso Msweli - 2016-04-17


Experience of 3 UKZN/Africa Centre students at the 7-week national bioinformatics workshop 2015

Author: Megan Druce, Zandile Sibisi & Sthembiso Msweli - 2015-04-23


15 minutes, All blogs...

Open access reports on HIV & TB drug resistance and bioinformatics in Africa HIV & TB Drug Resistance Clinical Cases Tutorial

SATuRN Collaborates on a Successful Molecular Diagnostics in HIV/AIDS and Tuberculosis in Zimbabwe, 6-9 Aug 2013

SATuRN 2013 report, date: 2013-08-21

Justen Manasa

SATuRN and Khethimpilo HIV Drug Resistance and Clinical Management Workshop Report, Durban, 11-12 July 2013

SATuRN 2013 report, date: 2013-08-01

Dean Solomon and Tulio de Oliveira

Major data analysis determines the trends of HIV-1 drug resistance mutations in South Africa.

SATuRN report 2013, date: 2013-07-01

Tulio de Oliveira

Transferring knowledge and skills to frontline medical personnel fighting the HIV & TB epidemics in rural South Africa

SATuRN 2013 report, date: 2013-03-16

Tulio de Oliveira, Justen Manasa, Richard Lessells

Bioafrica.net & SATuRN webpages received 186,746 visits in the past 12 months!

SATuRN 2013 report, date: 2013-02-26

Tulio de Oliveira

Clinical Case Study: The Diagnosis and Management of First-line Antiretroviral Treatment Failure

SATuRN 2012 report, date: 2013-01-16

Theresa Rossouw, Tulio de Oliveira & Richard Lessells

2nd Nurses and Health Care Workers Drug Resistance Training for the scale-up of resistance testing in the Free State Province, South Africa

SATuRN 2012 report, date: 2012-07-10

Dominique Goedhals & Cloete van Vuuren

SATuRN output, 15 minutes, All reports...

SATuRN output, 15 minutes, All cases...


Page design updated by Tulio de Oliveira, 2011