Southern African Treatment and Resistance Network (SATuRN)

SATuRN currently includes 24 research partners in southern Africa that support our initiatives. We have collated over 7,000 resistance genotypes linked to treatment and clinical information and host two of the best HIV drug resistance databases in the world (The Stanford HIV Drug Resistance Database and RegaDB Clinical Management and Drug resistance Database). To advance access to drug resistance testing to patients, providers and programs, we have been working with a network of academics laboratories to develop and implement a cheaper resistance genotype test. We have also delivered training in drug resistance testing and management to over 2,000 physician and nurses in southern Africa...


SATuRN Newsletters:
Information:

SATuRN newsletters:

Num 1 V.5 (Jan-Mar 2016)


Introduction:

SATuRN Mission/Vision

SATuRN Executive Summary

Who We Are: SATuRN Management, Participant Scientists, International Advisory Board, Funders


Information for Collaborators:

Manual of Operations (MoO) - reference to SATuRN organization, functions and access of data

Memorandum of Understanding (MoU) - deposit of data in SATuRN drug resistance databases (MSWord format)

Contributors Guidelines - website, newsletters and annual reports


Public Resources: HIV & TB Book and Online Databases

HIV & TB Drug Resistance and Clinical Management Casebook - Open access

SATuRN Stanford HIV Drug Resistance Database (HIVDB) -  Public Drug Resistance Databases in Southern Africa (de Oliveira et al. Nature 2010, 464:673)

SATuRN RegaDB Clinical Management Database - A Collaborative Clinical HIV Drug Resistance Database in Southern Africa


Open access pdf Publications (latest 5)

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration.
Rhee SY, Varghese V, Holmes SP, Van Zyl GU, Steegen K, Boyd MA, Cooper DA, Nsanzimana S, Saravanan S, Charpentier C, de Oliveira T, Etiebet MA, Garcia F, Goedhals D, Gomes P, Gunthard HF, Hamers RL, Hoffmann CJ, Hunt G, Jiamsakul A, Kaleebu P, Kanki P, Kantor R, Kerschberger B, Marconi VC, D'amour Ndahimana J, Ndembi N, Ngo-Giang-Huong N, Rokx C, Santoro MM, Schapiro JM, Schmidt D, Seu L, Sigaloff KCE, Sirivichayakul S, Skhosana L, Sunpath H, Tang M, Yang C, Carmona S, Gupta RK, Shafer RW., EBioMedicine (2017), :doi: 10.1016/j.ebiom.2017.03.024.

High Rates of Transmission of Drug-resistant HIV in Aruba Resulting in Reduced Susceptibility to the WHO Recommended First-line Regimen in Nearly Half of Newly Diagnosed HIV-infected Patients.
Hofstra LM, Rivas ES, Nijhuis M, Bank LEA, Wilkinson E, Kelly K, Mudrikova T, Schuurman R, de Oliveira T, de Kort J, Wensing AMJ, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix056.

Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis.
Collier D, Iwuji C, Derache A, de Oliveira T, Okesola N, Calmy A, Dabis F, Pillay D, Gupta RK, for ANRS 12249 TasP Study Group, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix015.

CD4+ T-cell count may not be a useful strategy to monitor antiretroviral therapy response in HTLV-1/HIV co-infected patients.
Vandormael A, Rego F, Danaviah S, Alcantara L, Boulware D, de Oliveira T, Current HIV Research (2017), :doi: 10.2174/1570162X15666170216114917.

Social disequilibrium and the risk of HIV acquisition: A multilevel study in rural KwaZulu-Natal Province, South Africa.
Tomita A, Vandormael AM, Barnighausen T, de Oliveira T, Tanser F, J Acquir Immune Defic Syndr. (2017), :10.1097/QAI.0000000000001349.

All publications - Bioinformatics, genomics and drug resistance peer-reviewed papers on HIV, TB and other pathogens
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News News Section, printed & online media on HIV & TB drug resistance and bioinformatics (latest 5)

KRISP Talks

A multi-centre analysis of internal migration and AIDS/TB and NCD-related mortality in Kenya and South Africa

KRISP Talks - 2017-08-23

KRISP Talks by Dr Carren Ginsburg, SAMRC/Wits Rural Public Health & Health Transitions Research Unit (Agincourt), 23 August 2017 (11am - midday), K-RITH building, Nelson R Mandela School of Medicine, UKZN, Durban, South Africa. All welcome!


KRISP News

KRISP & SANTHE trainee wins Best Abstract at DELTAS Africa meeting

KRISP News - 2017-07-19

Friday, 7 July, 2017, Dr Marcel Tongo Passo, a SANTHE Post-doctoral trainee, has won a "Best Abstract" award at the DELTAS (Developing Excellence in Leadership, Training and Science) Africa Annual Grantees Meeting 2017, held in Accra, Ghana, between 3 to 5 July. Passo is based at KRISP (KwaZulu-Natal Research and Innovation Sequencing Platform) and HPP (HIV Pathogenesis Programme) at the University of KwaZulu-Natal, South Africa.


KRISP News

Durban at the forefront of DNA research - KwaZulu-Natal Research and Innovation Sequencing Platform - KRISP

KRISP News - 2017-07-15

By Arthi Gopi, Independent on Saturday Newspaper - KRISP atrracts the brightest - Durban is leading the way in DNA research, having attracted some of the brightest minds in the science field, in a new state-of-the-art lab in the city.


KRISP News

KwaZulu-Natal Research and Innovation Sequencing Platform (KRISP) Established

KRISP News - 2017-07-12

The Technology Innovation Agency (TIA) and UKZN have signed an agreement for the establishment of KRISP - the KwaZulu-Natal Research and Innovation Sequencing Platform.


KRISP Talks

Seminar: Can the type of jeans you wear determine your treatment response?

KRISP Talks - 2017-06-23

KRISP Talks by Professor Bonga Chiliza, Discipline of Psychiatry: College of Health Sciences, UKZN, 23 June 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa. All welcome!


All news...
Blogs on bioinformatics, HIV & TB drug resistance, treatment, community engagement and bioinformatics in Africa Twitter

Megan Druce: from Cum Laude MSc to a Scholarship for a PhD in Germany...

Author: Megan Druce - 2016-04-18


Sthembiso Msweli: from Hlabisa to MSc and Further Promoted to Laboratory Manager...

Author: Sthembiso Msweli - 2016-04-17


Experience of 3 UKZN/Africa Centre students at the 7-week national bioinformatics workshop 2015

Author: Megan Druce, Zandile Sibisi & Sthembiso Msweli - 2015-04-23


Tale of 4 Cities in outlining researcher's strive towards a cure for HIV

Author: Siva Danaviah - 2014-10-14


Massive Open Online Courses: Huge potential for bioinformatics education

Author: Rachael Dellar - 2014-10-13


15 minutes, All blogs...

Open access reports on HIV & TB drug resistance and bioinformatics in Africa HIV & TB Drug Resistance Clinical Cases Tutorial

SATuRN Collaborates on a Successful Molecular Diagnostics in HIV/AIDS and Tuberculosis in Zimbabwe, 6-9 Aug 2013

SATuRN 2013 report, date: 2013-08-21

Justen Manasa

SATuRN and Khethimpilo HIV Drug Resistance and Clinical Management Workshop Report, Durban, 11-12 July 2013

SATuRN 2013 report, date: 2013-08-01

Dean Solomon and Tulio de Oliveira

Major data analysis determines the trends of HIV-1 drug resistance mutations in South Africa.

SATuRN report 2013, date: 2013-07-01

Tulio de Oliveira

Transferring knowledge and skills to frontline medical personnel fighting the HIV & TB epidemics in rural South Africa

SATuRN 2013 report, date: 2013-03-16

Tulio de Oliveira, Justen Manasa, Richard Lessells

Bioafrica.net & SATuRN webpages received 186,746 visits in the past 12 months!

SATuRN 2013 report, date: 2013-02-26

Tulio de Oliveira

Clinical Case Study: The Diagnosis and Management of First-line Antiretroviral Treatment Failure

SATuRN 2012 report, date: 2013-01-16

Theresa Rossouw, Tulio de Oliveira & Richard Lessells

2nd Nurses and Health Care Workers Drug Resistance Training for the scale-up of resistance testing in the Free State Province, South Africa

SATuRN 2012 report, date: 2012-07-10

Dominique Goedhals & Cloete van Vuuren

SATuRN output, 15 minutes, All reports...

SATuRN output, 15 minutes, All cases...


Page design updated by Tulio de Oliveira, 2011